Multimodal confusion

Kevin Rudd likened the GFC to a faecal meteorological event and the recent exposure of Scott Reuben as a fraudster warrants the same analogy. Reuben's publications have encouraged the use of NSAIDs, COX2 inhibitors, clonidine and controlled release oxycodone in the perioperative acute pain setting, and their use have been encouraged by authoritative guidelines. But it could be all back to square one for the clinical science of acute pain, particularly as the association of NSAIDs and COX2Is with a range of harmful effects make their use difficult to justify without good evidence.
We await the editorials in the May edition of Anesthesia Analgesia.